2025 American Conference Leaders Passes Defended - Games in November Only through 12/20/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | East Carolina | 5 | 6 | 14 | 20 | 4.00 |
| 2 | Florida Atlantic | 4 | 3 | 16 | 19 | 4.75 |
| 3 | North Texas | 4 | 6 | 11 | 17 | 4.25 |
| 3 | Tulane | 4 | 6 | 11 | 17 | 4.25 |
| 3 | USF | 4 | 4 | 13 | 17 | 4.25 |
| 6 | Charlotte | 4 | 4 | 12 | 16 | 4.00 |
| 7 | Army | 4 | 3 | 9 | 12 | 3.00 |
| 8 | Tulsa | 4 | 2 | 8 | 10 | 2.50 |
| 8 | UAB | 5 | 1 | 9 | 10 | 2.00 |
| 10 | Rice | 3 | 0 | 9 | 9 | 3.00 |
| 10 | UTSA | 4 | 2 | 7 | 9 | 2.25 |
| 12 | Temple | 4 | 1 | 7 | 8 | 2.00 |
| 13 | Memphis | 3 | 0 | 7 | 7 | 2.33 |
| 13 | Navy | 4 | 1 | 6 | 7 | 1.75 |