2025 American Conference Leaders Passes Defended - Games vs. Non-Conference Teams Only through 10/31/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Memphis | 4 | 6 | 17 | 23 | 5.75 |
| 2 | Tulane | 4 | 5 | 17 | 22 | 5.50 |
| 3 | UTSA | 4 | 3 | 17 | 20 | 5.00 |
| 4 | East Carolina | 4 | 3 | 16 | 19 | 4.75 |
| 4 | Temple | 4 | 3 | 16 | 19 | 4.75 |
| 6 | Rice | 4 | 1 | 16 | 17 | 4.25 |
| 7 | Florida Atlantic | 3 | 0 | 15 | 15 | 5.00 |
| 7 | USF | 4 | 4 | 11 | 15 | 3.75 |
| 9 | UAB | 3 | 1 | 13 | 14 | 4.67 |
| 10 | North Texas | 4 | 5 | 8 | 13 | 3.25 |
| 11 | Army | 2 | 1 | 10 | 11 | 5.50 |
| 11 | Tulsa | 3 | 1 | 10 | 11 | 3.67 |
| 13 | Charlotte | 3 | 0 | 7 | 7 | 2.33 |
| 14 | Navy | 2 | 0 | 5 | 5 | 2.50 |