2025 American Conference Leaders Passes Defended - Games vs. FBS Teams With Winning Record Only through 09/12/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | UTSA | 2 | 1 | 6 | 7 | 3.50 |
| 2 | Florida Atlantic | 1 | 0 | 6 | 6 | 6.00 |
| 2 | Rice | 1 | 0 | 6 | 6 | 6.00 |
| 4 | East Carolina | 1 | 1 | 3 | 4 | 4.00 |
| 4 | Tulsa | 1 | 0 | 4 | 4 | 4.00 |
| 6 | Charlotte | 1 | 0 | 3 | 3 | 3.00 |