2020 Atlantic Coast Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 2 | 392 | 431 | 128 | 823 | 6.43 | 411.5 |
| 2 | Pittsburgh | 4 | 431 | 1313 | 321 | 1744 | 5.43 | 436.0 |
| 3 | Notre Dame | 4 | 480 | 1269 | 255 | 1749 | 6.86 | 437.3 |
| 4 | Georgia Tech | 3 | 486 | 1008 | 226 | 1494 | 6.61 | 498.0 |
| 5 | Virginia | 4 | 531 | 1278 | 276 | 1809 | 6.55 | 452.3 |
| 6 | North Carolina | 4 | 533 | 1108 | 252 | 1641 | 6.51 | 410.3 |
| 7 | Boston College | 3 | 556 | 850 | 216 | 1406 | 6.51 | 468.7 |
| 8 | Clemson | 4 | 595 | 1035 | 263 | 1630 | 6.20 | 407.5 |
| 9 | North Carolina State | 3 | 622 | 855 | 237 | 1477 | 6.23 | 492.3 |
| 10 | Wake Forest | 3 | 647 | 1119 | 238 | 1766 | 7.42 | 588.7 |
| 11 | Duke | 4 | 843 | 1050 | 286 | 1893 | 6.62 | 473.3 |
| 12 | Florida State | 4 | 885 | 1157 | 306 | 2042 | 6.67 | 510.5 |
| 13 | Miami (Florida) | 3 | 943 | 795 | 226 | 1738 | 7.69 | 579.3 |
| 14 | Syracuse | 5 | 1023 | 1391 | 374 | 2414 | 6.45 | 482.8 |
| 15 | Virginia Tech | 5 | 1156 | 1171 | 359 | 2327 | 6.48 | 465.4 |