2025 Atlantic Coast Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 09/11/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | California | 1 | 65 | 248 | 61 | 313 | 5.13 | 313.0 |
| 2 | Florida State | 1 | 87 | 254 | 72 | 341 | 4.74 | 341.0 |
| 3 | Clemson | 1 | 108 | 248 | 70 | 356 | 5.09 | 356.0 |
| 4 | Duke | 1 | 123 | 296 | 73 | 419 | 5.74 | 419.0 |
| 5 | Georgia Tech | 1 | 146 | 159 | 60 | 305 | 5.08 | 305.0 |
| 6 | Boston College | 1 | 149 | 231 | 64 | 380 | 5.94 | 380.0 |
| 7 | Stanford | 1 | 157 | 175 | 68 | 332 | 4.88 | 332.0 |
| 8 | SMU | 1 | 161 | 440 | 94 | 601 | 6.39 | 601.0 |
| 9 | Wake Forest | 1 | 205 | 201 | 76 | 406 | 5.34 | 406.0 |
| 10 | Virginia | 1 | 216 | 200 | 58 | 416 | 7.17 | 416.0 |
| 11 | Syracuse | 1 | 246 | 247 | 68 | 493 | 7.25 | 493.0 |
| 12 | North Carolina | 1 | 258 | 284 | 72 | 542 | 7.53 | 542.0 |
| 13 | NC State | 2 | 316 | 509 | 132 | 825 | 6.25 | 412.5 |
| 14 | Virginia Tech | 2 | 381 | 437 | 113 | 818 | 7.24 | 409.0 |