2025 Atlantic Coast Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 12/06/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | NC State | 3 | 240 | 846 | 210 | 1086 | 5.17 | 362.0 |
| 2 | Virginia | 3 | 285 | 550 | 178 | 835 | 4.69 | 278.3 |
| 3 | Clemson | 4 | 293 | 1057 | 264 | 1350 | 5.11 | 337.5 |
| 4 | Miami (FL) | 4 | 305 | 673 | 229 | 978 | 4.27 | 244.5 |
| 5 | California | 4 | 382 | 779 | 241 | 1161 | 4.82 | 290.3 |
| 6 | Wake Forest | 4 | 393 | 761 | 308 | 1154 | 3.75 | 288.5 |
| 7 | Boston College | 4 | 417 | 1044 | 243 | 1461 | 6.01 | 365.3 |
| 8 | Pittsburgh | 4 | 426 | 820 | 284 | 1246 | 4.39 | 311.5 |
| 9 | Louisville | 4 | 430 | 444 | 233 | 874 | 3.75 | 218.5 |
| 10 | SMU | 4 | 459 | 1338 | 314 | 1797 | 5.72 | 449.3 |
| 11 | Stanford | 4 | 491 | 1195 | 278 | 1686 | 6.06 | 421.5 |
| 12 | Florida State | 4 | 507 | 677 | 245 | 1184 | 4.83 | 296.0 |
| 13 | North Carolina | 4 | 546 | 832 | 272 | 1378 | 5.07 | 344.5 |
| 14 | Duke | 4 | 598 | 994 | 269 | 1592 | 5.92 | 398.0 |
| 15 | Virginia Tech | 4 | 630 | 855 | 225 | 1485 | 6.60 | 371.3 |
| 16 | Georgia Tech | 4 | 637 | 582 | 285 | 1219 | 4.28 | 304.8 |
| 17 | Syracuse | 4 | 824 | 891 | 268 | 1715 | 6.40 | 428.8 |