2025 Big 12 Conference Leaders Long All Purpose Plays - Games vs. FBS Teams With Winning Record Only through 11/18/2025
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Emmanuel Henderson Jr. | Kansas | SR | WR | 5 | 2 | 2 | 2 | 2 | 2 | 1 | 1 |
| 2 | Cyrus Allen | Cincinnati | SR | WR | 4 | 3 | 2 | 1 | 1 | 1 | 1 | 0 |
| 2 | Cyncir Bowers | WVU | SO | RB | 5 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 2 | Jayce Brown | Kansas St | JR | WR | 5 | 5 | 2 | 2 | 1 | 1 | 0 | 0 |
| 2 | Mana Carvalho | Utah | FR | WR | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Brett Eskildsen | Iowa State | SO | WR | 6 | 4 | 3 | 1 | 1 | 1 | 0 | 0 |
| 2 | Aiden Flora | Iowa State | FR | RB | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Caleb Goodie | Cincinnati | JR | WR | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 2 | Parker Kingston | BYU | JR | WR | 6 | 3 | 2 | 1 | 1 | 1 | 0 | 0 |
| 2 | Eric McAlister | TCU | SR | WR | 4 | 5 | 4 | 1 | 1 | 1 | 0 | 0 |
| 2 | Omarion Miller | Colorado | JR | WR | 7 | 6 | 2 | 2 | 1 | 1 | 0 | 0 |
| 2 | Bryce Noernberg | Kansas St | FR | WR | 4 | 2 | 2 | 1 | 1 | 1 | 1 | 1 |
| 2 | Jordan Scruggs | WVU | SR | CB | 7 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 2 | Jeff Sims | Ariz St | SR | QB | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 2 | Tre Spivey | Arizona | SO | WR | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 2 | Jeff Weimer | WVU | SR | WR | 7 | 3 | 2 | 2 | 1 | 1 | 0 | 0 |
| 2 | J'Koby Williams | Texas Tech | SO | RB | 4 | 4 | 3 | 2 | 1 | 1 | 0 | 0 |