2025 Conference USA Leaders Sacks - Games vs. FBS non-Power 5 Conference Teams Only through 09/13/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | UTEP | 1 | 6.0 | 34 | 6.00 |
| 1 | Sam Houston State | 3 | 6.0 | 34 | 2.00 |
| 3 | Jacksonville State | 2 | 4.0 | 26 | 2.00 |
| 4 | Middle Tennessee State | 1 | 3.0 | 23 | 3.00 |
| 5 | FIU | 1 | 2.0 | 19 | 2.00 |
| 6 | New Mexico State | 2 | 3.0 | 15 | 1.50 |
| 7 | Western Kentucky | 2 | 2.0 | 12 | 1.00 |
| 8 | Louisiana Tech | 1 | 1.0 | 11 | 1.00 |
| 9 | Missouri State | 1 | 1.0 | 6 | 1.00 |
| 10 | Liberty | 2 | 1.0 | 5 | 0.50 |
| 11 | Delaware | 1 | 1.0 | 4 | 1.00 |