2025 Conference USA Leaders Sacks - Games in August/September Only through 11/22/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | UTEP | 5 | 15.0 | 110 | 3.00 |
| 2 | Louisiana Tech | 5 | 10.0 | 77 | 2.00 |
| 3 | Jacksonville State | 5 | 10.0 | 75 | 2.00 |
| 4 | Delaware | 4 | 10.0 | 72 | 2.50 |
| 5 | FIU | 4 | 8.0 | 58 | 2.00 |
| 6 | Missouri State | 5 | 7.0 | 51 | 1.40 |
| 7 | Middle Tennessee State | 5 | 10.0 | 50 | 2.00 |
| 8 | Kennesaw State | 5 | 10.0 | 41 | 2.00 |
| 9 | Western Kentucky | 5 | 6.0 | 37 | 1.20 |
| 10 | New Mexico State | 4 | 6.0 | 36 | 1.50 |
| 11 | Sam Houston State | 4 | 7.0 | 35 | 1.75 |
| 12 | Liberty | 5 | 5.0 | 30 | 1.00 |