2025 Conference USA Leaders Sacks - Games vs. FBS Teams With Non-Winning Record Only through 11/01/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Jacksonville State | 6 | 13.0 | 71 | 2.17 |
| 2 | UTEP | 4 | 10.0 | 62 | 2.50 |
| 3 | Delaware | 4 | 8.0 | 50 | 2.00 |
| 3 | Missouri State | 4 | 7.0 | 50 | 1.75 |
| 5 | Middle Tennessee State | 4 | 8.0 | 44 | 2.00 |
| 6 | Western Kentucky | 6 | 6.0 | 39 | 1.00 |
| 7 | Liberty | 4 | 7.0 | 37 | 1.75 |
| 7 | New Mexico State | 3 | 6.0 | 37 | 2.00 |
| 9 | FIU | 3 | 5.0 | 34 | 1.67 |
| 10 | Kennesaw State | 3 | 6.0 | 29 | 2.00 |
| 11 | Louisiana Tech | 3 | 3.0 | 21 | 1.00 |
| 12 | Sam Houston State | 2 | 2.0 | 16 | 1.00 |