2025 Conference USA Leaders Rushing Defense - Games in October Only through 10/08/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Middle Tennessee State | 1 | 35 | 70 | 2.00 | 1 | 35.00 | 70.00 |
| 2 | Liberty | 1 | 25 | 56 | 2.24 | 1 | 25.00 | 56.00 |
| 3 | New Mexico State | 1 | 26 | 69 | 2.65 | 0 | 26.00 | 69.00 |
| 4 | Sam Houston State | 1 | 31 | 95 | 3.06 | 2 | 31.00 | 95.00 |
| 5 | UTEP | 1 | 50 | 160 | 3.20 | 1 | 50.00 | 160.00 |
| 6 | Missouri State | 1 | 25 | 86 | 3.44 | 0 | 25.00 | 86.00 |
| 7 | Western Kentucky | 1 | 34 | 121 | 3.56 | 3 | 34.00 | 121.00 |
| 8 | Delaware | 1 | 26 | 108 | 4.15 | 1 | 26.00 | 108.00 |
| 9 | FIU | 1 | 33 | 150 | 4.55 | 2 | 33.00 | 150.00 |