2025 Conference USA Leaders Rushing Defense - Games Lost Only through 12/13/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 5 | 162 | 603 | 3.72 | 7 | 32.40 | 120.60 |
| 2 | Middle Tennessee State | 9 | 354 | 1352 | 3.82 | 16 | 39.33 | 150.22 |
| 3 | Jacksonville State | 5 | 206 | 826 | 4.01 | 8 | 41.20 | 165.20 |
| 4 | UTEP | 10 | 416 | 1799 | 4.32 | 16 | 41.60 | 179.90 |
| 5 | New Mexico State | 8 | 319 | 1454 | 4.56 | 11 | 39.88 | 181.75 |
| 6 | Liberty | 8 | 334 | 1687 | 5.05 | 19 | 41.75 | 210.88 |
| 7 | FIU | 5 | 173 | 919 | 5.31 | 11 | 34.60 | 183.80 |
| 8 | Delaware | 6 | 219 | 1177 | 5.37 | 17 | 36.50 | 196.17 |
| 9 | Kennesaw State | 3 | 128 | 695 | 5.43 | 7 | 42.67 | 231.67 |
| 10 | Missouri State | 5 | 189 | 1060 | 5.61 | 17 | 37.80 | 212.00 |
| 11 | Sam Houston State | 10 | 382 | 2208 | 5.78 | 29 | 38.20 | 220.80 |
| 12 | Western Kentucky | 4 | 166 | 975 | 5.87 | 5 | 41.50 | 243.75 |