2022 Conference USA Leaders Rushing Defense - Games in October Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UTSA | 3 | 81 | 267 | 3.30 | 3 | 27.00 | 89.00 |
| 2 | UTEP | 4 | 133 | 492 | 3.70 | 2 | 33.25 | 123.00 |
| 3 | Rice | 4 | 176 | 690 | 3.92 | 5 | 44.00 | 172.50 |
| 4 | North Texas | 4 | 151 | 620 | 4.11 | 4 | 37.75 | 155.00 |
| 5 | Florida International | 5 | 182 | 751 | 4.13 | 11 | 36.40 | 150.20 |
| 6 | UAB | 5 | 178 | 744 | 4.18 | 7 | 35.60 | 148.80 |
| 7 | Western Kentucky | 5 | 185 | 838 | 4.53 | 7 | 37.00 | 167.60 |
| 8 | Charlotte | 4 | 171 | 830 | 4.85 | 7 | 42.75 | 207.50 |
| 9 | Middle Tennessee | 3 | 108 | 569 | 5.27 | 6 | 36.00 | 189.67 |
| 10 | Florida Atlantic | 4 | 157 | 878 | 5.59 | 5 | 39.25 | 219.50 |
| 11 | Louisiana Tech | 4 | 156 | 992 | 6.36 | 11 | 39.00 | 248.00 |