2025 Conference USA Leaders Opponent First Downs - Games vs. Unranked Teams Only (AP Poll) through 09/06/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | FIU | 1 | 7 | 10 | 0 | 17 | 17.0 |
| 2 | Louisiana Tech | 1 | 11 | 5 | 2 | 18 | 18.0 |
| 3 | Kennesaw State | 1 | 9 | 10 | 1 | 20 | 20.0 |
| 4 | Liberty | 2 | 21 | 12 | 0 | 33 | 16.5 |
| 5 | UTEP | 2 | 12 | 22 | 3 | 37 | 18.5 |
| 6 | Missouri State | 2 | 15 | 19 | 5 | 39 | 19.5 |
| 7 | Middle Tennessee State | 2 | 15 | 22 | 3 | 40 | 20.0 |
| 8 | New Mexico State | 2 | 11 | 25 | 5 | 41 | 20.5 |
| 9 | Delaware | 2 | 17 | 21 | 4 | 42 | 21.0 |
| 10 | Jacksonville State | 2 | 19 | 22 | 2 | 43 | 21.5 |
| 11 | Western Kentucky | 3 | 22 | 21 | 9 | 52 | 17.3 |
| 12 | Sam Houston State | 3 | 18 | 47 | 5 | 70 | 23.3 |