2025 Conference USA Leaders Total Defense - Games at Home Only through 11/12/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Sam Houston State | 3 | 700 | 614 | 196 | 1314 | 6.70 | 438.0 |
| 2 | Western Kentucky | 5 | 848 | 795 | 341 | 1643 | 4.82 | 328.6 |
| 3 | Jacksonville State | 3 | 325 | 898 | 206 | 1223 | 5.94 | 407.7 |
| 4 | Missouri State | 4 | 512 | 979 | 266 | 1491 | 5.61 | 372.8 |
| 5 | UTEP | 5 | 856 | 1005 | 354 | 1861 | 5.26 | 372.2 |
| 6 | Kennesaw State | 5 | 597 | 1075 | 359 | 1672 | 4.66 | 334.4 |
| 7 | FIU | 4 | 594 | 1079 | 275 | 1673 | 6.08 | 418.3 |
| 8 | New Mexico State | 5 | 612 | 1167 | 360 | 1779 | 4.94 | 355.8 |
| 9 | Middle Tennessee State | 5 | 692 | 1204 | 347 | 1896 | 5.46 | 379.2 |
| 10 | Delaware | 5 | 717 | 1208 | 326 | 1925 | 5.90 | 385.0 |
| 11 | Liberty | 5 | 679 | 1217 | 337 | 1896 | 5.63 | 379.2 |
| 12 | Louisiana Tech | 5 | 683 | 1254 | 352 | 1937 | 5.50 | 387.4 |