2025 Conference USA Leaders Passes Defended - Games vs. FBS Teams With Winning Record Only through 11/01/2025
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jessiah McGrew | FIU | FR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 1 | Naeten Mitchell | NMSU | SO | S | 4 | 2 | 1 | 3 | 0.75 |
| 1 | Emon Allen | Sam Hou St | SR | DB | 6 | 2 | 1 | 3 | 0.50 |
| 4 | Mister Clark | FIU | SO | DB | 4 | 1 | 5 | 6 | 1.50 |
| 4 | Jaavan Mack | Western Ky | SR | DB | 2 | 1 | 3 | 4 | 2.00 |
| 4 | Xavier Smith | UTEP | JR | S | 3 | 1 | 3 | 4 | 1.33 |
| 4 | Sone Aupiu | NMSU | JR | LB | 3 | 1 | 2 | 3 | 1.00 |
| 4 | Justin Content | UTEP | SO | CB | 3 | 1 | 2 | 3 | 1.00 |
| 4 | Antonio Stevens | KSU | SR | DB | 4 | 1 | 2 | 3 | 0.75 |
| 4 | Alonzo Edwards Jr. | Sam Hou St | SR | DB | 6 | 1 | 2 | 3 | 0.50 |
| 4 | Tyler Martinez | NMSU | SR | LB | 2 | 1 | 1 | 2 | 1.00 |
| 4 | Kody Jones | KSU | SR | DB | 3 | 1 | 1 | 2 | 0.67 |
| 4 | Michael Richard | La Tech | JR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 4 | Kameron Carter | La Tech | JR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 4 | Kolbe Fields | La Tech | SR | LB | 2 | 1 | 0 | 1 | 0.50 |
| 4 | J.J. O'Neal | MO State | SR | S | 2 | 1 | 0 | 1 | 0.50 |
| 4 | Brylan Green | Liberty | SR | S | 3 | 1 | 0 | 1 | 0.33 |
| 4 | A'Khori Jones | Liberty | SR | S | 3 | 1 | 0 | 1 | 0.33 |
| 4 | Jayden Wilson | UTEP | JR | LB | 3 | 1 | 0 | 1 | 0.33 |