2025 Conference USA Leaders Passes Defended - Games in October Only through 11/01/2025
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Naeten Mitchell | NMSU | SO | S | 3 | 3 | 3 | 6 | 2.00 |
| 2 | Jessiah McGrew | FIU | FR | DB | 4 | 2 | 2 | 4 | 1.00 |
| 3 | Jordan Dunbar | MO State | SR | CB | 3 | 1 | 5 | 6 | 2.00 |
| 3 | Mister Clark | FIU | SO | DB | 4 | 1 | 5 | 6 | 1.50 |
| 3 | Zedekiah Rodriguez-Brown | NMSU | SR | CB | 3 | 1 | 3 | 4 | 1.33 |
| 3 | Antonio Stevens | KSU | SR | DB | 3 | 1 | 3 | 4 | 1.33 |
| 3 | Muaaz Byard | MTSU | JR | OLB | 3 | 1 | 2 | 3 | 1.00 |
| 3 | Josiah Charles | NMSU | SO | CB | 3 | 1 | 2 | 3 | 1.00 |
| 3 | Maguire Neal | MO State | SR | S | 3 | 1 | 2 | 3 | 1.00 |
| 3 | Jaavan Mack | Western Ky | SR | DB | 3 | 1 | 2 | 3 | 1.00 |
| 3 | Kameron Carter | La Tech | JR | DB | 3 | 1 | 1 | 2 | 0.67 |
| 3 | Dylan Dixson | MO State | JR | NB | 3 | 1 | 1 | 2 | 0.67 |
| 3 | Kody Jones | KSU | SR | DB | 3 | 1 | 1 | 2 | 0.67 |
| 3 | Alonzo Edwards Jr. | Sam Hou St | SR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 3 | Eldric Griffin | Liberty | SR | S | 2 | 1 | 0 | 1 | 0.50 |
| 3 | Jiquavious Marshall | Liberty | FR | CB | 2 | 1 | 0 | 1 | 0.50 |
| 3 | KT Seay | Delaware | JR | S | 3 | 1 | 0 | 1 | 0.33 |
| 3 | Caleb Nix | J'ville St | JR | SAF | 3 | 1 | 0 | 1 | 0.33 |
| 3 | Jacob Fields | La Tech | JR | DB | 3 | 1 | 0 | 1 | 0.33 |
| 3 | Thomas Anderson | MO State | SR | CB | 3 | 1 | 0 | 1 | 0.33 |
| 3 | Jayden Wilson | UTEP | JR | LB | 3 | 1 | 0 | 1 | 0.33 |
| 3 | Koron Hayward | Western Ky | SO | LB | 3 | 1 | 0 | 1 | 0.33 |
| 3 | Emon Allen | Sam Hou St | SR | DB | 4 | 1 | 0 | 1 | 0.25 |