2022 Conference USA Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UTEP | 11 | 1373 | 2365 | 660 | 3738 | 5.66 | 339.8 |
| 2 | UAB | 11 | 1790 | 2098 | 735 | 3888 | 5.29 | 353.5 |
| 3 | Charlotte | 9 | 1678 | 2412 | 626 | 4090 | 6.53 | 454.4 |
| 4 | Western Kentucky | 11 | 1541 | 2656 | 804 | 4197 | 5.22 | 381.5 |
| 5 | Louisiana Tech | 9 | 2171 | 2070 | 641 | 4241 | 6.62 | 471.2 |
| 6 | Rice | 11 | 1983 | 2291 | 675 | 4274 | 6.33 | 388.5 |
| 7 | UTSA | 12 | 1475 | 3018 | 837 | 4493 | 5.37 | 374.4 |
| 8 | Florida Atlantic | 10 | 1916 | 2581 | 721 | 4497 | 6.24 | 449.7 |
| 9 | Middle Tennessee | 11 | 1397 | 3349 | 817 | 4746 | 5.81 | 431.5 |
| 10 | Florida International | 11 | 2180 | 2773 | 819 | 4953 | 6.05 | 450.3 |
| 11 | North Texas | 13 | 2550 | 3430 | 983 | 5980 | 6.08 | 460.0 |