2022 Conference USA Leaders Total Defense - Games at Home Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UTEP | 6 | 727 | 925 | 351 | 1652 | 4.71 | 275.3 |
| 2 | Middle Tennessee | 5 | 530 | 1452 | 371 | 1982 | 5.34 | 396.4 |
| 3 | Rice | 6 | 1010 | 1009 | 341 | 2019 | 5.92 | 336.5 |
| 4 | UAB | 6 | 879 | 1195 | 422 | 2074 | 4.91 | 345.7 |
| 5 | Western Kentucky | 6 | 945 | 1168 | 400 | 2113 | 5.28 | 352.2 |
| 6 | Louisiana Tech | 5 | 1204 | 1006 | 374 | 2210 | 5.91 | 442.0 |
| 7 | Florida Atlantic | 6 | 925 | 1557 | 412 | 2482 | 6.02 | 413.7 |
| 8 | Florida International | 6 | 1179 | 1398 | 467 | 2577 | 5.52 | 429.5 |
| 9 | North Texas | 6 | 885 | 1758 | 426 | 2643 | 6.20 | 440.5 |
| 10 | UTSA | 7 | 1042 | 1719 | 477 | 2761 | 5.79 | 394.4 |
| 11 | Charlotte | 6 | 1163 | 1828 | 389 | 2991 | 7.69 | 498.5 |