2021 American Athletic Conference Leaders Interceptions - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Malik Fleming | ECU | SO | CB | 5 | 1 | 31 | 1 | 0.20 |
| 1 | Manny Walker | Temple | SR | DE | 6 | 1 | 7 | 1 | 0.17 |
| 1 | Alex Hogan | Houston | JR | CB | 8 | 1 | 91 | 1 | 0.13 |