2021 Big 12 Conference Leaders Interceptions - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Al Walcott | Baylor | JR | CB | 2 | 1 | 96 | 1 | 0.50 |
| 2 | JT Woods | Baylor | SR | S | 2 | 3 | 49 | 0 | 1.50 |
| 3 | Ross Elder | Kansas St | SR | DB | 1 | 1 | 32 | 0 | 1.00 |
| 4 | Brayden Utley | Baylor | JR | DL | 2 | 1 | 15 | 0 | 0.50 |
| 5 | Justin Broiles | Oklahoma | SR | DB | 1 | 1 | 12 | 0 | 1.00 |
| 6 | Malcolm Rodriguez | Okla St | SR | LB | 2 | 1 | 11 | 0 | 0.50 |