2018 American Athletic Conference Leaders Sacks - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Temple | 3 | 12.0 | 50 | 4.00 |
| 2 | South Florida | 2 | 7.0 | 44 | 3.50 |
| 3 | Cincinnati | 2 | 6.0 | 26 | 3.00 |
| 4 | UCF | 2 | 5.0 | 24 | 2.50 |
| 5 | Tulane | 2 | 4.0 | 14 | 2.00 |
| 6 | Memphis | 2 | 2.0 | 13 | 1.00 |
| 6 | Houston | 2 | 2.0 | 11 | 1.00 |
| 8 | East Carolina | 2 | 1.0 | 9 | 0.50 |
| 8 | Connecticut | 1 | 1.0 | 7 | 1.00 |
| 8 | SMU | 2 | 1.0 | 1 | 0.50 |