2016 American Athletic Conference Leaders Sacks - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Houston | 2 | 16.0 | 103 | 8.00 |
| 2 | South Florida | 3 | 9.0 | 60 | 3.00 |
| 3 | UCF | 2 | 7.0 | 47 | 3.50 |
| 4 | Connecticut | 3 | 4.0 | 36 | 1.33 |
| 5 | Temple | 2 | 3.0 | 23 | 1.50 |
| 6 | SMU | 2 | 2.0 | 22 | 1.00 |
| 6 | Memphis | 2 | 2.0 | 12 | 1.00 |
| 8 | East Carolina | 3 | 1.0 | 8 | 0.33 |
| 8 | Tulsa | 1 | 1.0 | 4 | 1.00 |
| 8 | Tulane | 1 | 1.0 | 3 | 1.00 |