2018 American Athletic Conference Leaders Sacks - Games vs. FBS non-Power 5 Conference Teams Only through 01/07/2019
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Tulane | 10 | 35.0 | 227 | 3.50 |
| 2 | Memphis | 11 | 31.0 | 210 | 2.82 |
| 2 | East Carolina | 9 | 31.0 | 186 | 3.44 |
| 4 | Cincinnati | 10 | 23.0 | 165 | 2.30 |
| 5 | Temple | 9 | 22.0 | 156 | 2.44 |
| 5 | SMU | 9 | 22.0 | 142 | 2.44 |
| 7 | Houston | 10 | 20.0 | 129 | 2.00 |
| 7 | UCF | 10 | 20.0 | 127 | 2.00 |
| 9 | South Florida | 10 | 19.0 | 97 | 1.90 |
| 10 | Tulsa | 9 | 13.0 | 97 | 1.44 |
| 11 | Navy | 12 | 9.0 | 80 | 0.75 |
| 12 | Connecticut | 10 | 7.0 | 37 | 0.70 |