2025 Atlantic Coast Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 12/06/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Miami (FL) | 9 | 817 | 1679 | 562 | 2496 | 4.44 | 277.3 |
| 2 | Louisville | 9 | 927 | 1943 | 587 | 2870 | 4.89 | 318.9 |
| 3 | Syracuse | 9 | 1521 | 2389 | 589 | 3910 | 6.64 | 434.4 |
| 4 | NC State | 9 | 1415 | 2551 | 608 | 3966 | 6.52 | 440.7 |
| 5 | Stanford | 9 | 1097 | 2447 | 616 | 3544 | 5.75 | 393.8 |
| 6 | Boston College | 9 | 1863 | 2255 | 618 | 4118 | 6.66 | 457.6 |
| 7 | Wake Forest | 9 | 1208 | 1810 | 627 | 3018 | 4.81 | 335.3 |
| 8 | Pittsburgh | 9 | 912 | 2322 | 632 | 3234 | 5.12 | 359.3 |
| 9 | Georgia Tech | 10 | 1735 | 2375 | 653 | 4110 | 6.29 | 411.0 |
| 10 | Clemson | 10 | 1090 | 2578 | 662 | 3668 | 5.54 | 366.8 |
| 11 | Virginia Tech | 10 | 1590 | 2280 | 663 | 3870 | 5.84 | 387.0 |
| 12 | California | 10 | 1756 | 2039 | 668 | 3795 | 5.68 | 379.5 |
| 13 | Duke | 10 | 1345 | 2802 | 674 | 4147 | 6.15 | 414.7 |
| 14 | Florida State | 10 | 1509 | 2034 | 683 | 3543 | 5.19 | 354.3 |
| 15 | North Carolina | 10 | 1363 | 2210 | 684 | 3573 | 5.22 | 357.3 |
| 16 | Virginia | 11 | 1286 | 2270 | 706 | 3556 | 5.04 | 323.3 |
| 17 | SMU | 10 | 1111 | 2897 | 756 | 4008 | 5.30 | 400.8 |