2025 Atlantic Coast Conference Leaders Total Defense - Games on the Road/Neutral Site Only through 12/06/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 4 | 485 | 913 | 252 | 1398 | 5.55 | 349.5 |
| 2 | Miami (FL) | 4 | 379 | 1037 | 268 | 1416 | 5.28 | 354.0 |
| 3 | Clemson | 5 | 501 | 1150 | 311 | 1651 | 5.31 | 330.2 |
| 4 | Boston College | 5 | 1040 | 1000 | 329 | 2040 | 6.20 | 408.0 |
| 5 | Wake Forest | 5 | 709 | 989 | 338 | 1698 | 5.02 | 339.6 |
| 6 | Georgia Tech | 5 | 842 | 1467 | 340 | 2309 | 6.79 | 461.8 |
| 7 | Virginia Tech | 5 | 880 | 1039 | 342 | 1919 | 5.61 | 383.8 |
| 8 | NC State | 5 | 671 | 1653 | 343 | 2324 | 6.78 | 464.8 |
| 9 | Florida State | 5 | 847 | 931 | 351 | 1778 | 5.07 | 355.6 |
| 10 | Pittsburgh | 5 | 531 | 1234 | 362 | 1765 | 4.88 | 353.0 |
| 11 | California | 6 | 1042 | 1076 | 374 | 2118 | 5.66 | 353.0 |
| 12 | Syracuse | 6 | 1153 | 1536 | 379 | 2689 | 7.09 | 448.2 |
| 13 | Stanford | 6 | 830 | 1424 | 386 | 2254 | 5.84 | 375.7 |
| 14 | Virginia | 6 | 602 | 1401 | 392 | 2003 | 5.11 | 333.8 |
| 15 | North Carolina | 6 | 765 | 1118 | 394 | 1883 | 4.78 | 313.8 |
| 16 | SMU | 6 | 531 | 1801 | 448 | 2332 | 5.21 | 388.7 |
| 17 | Duke | 7 | 842 | 1865 | 452 | 2707 | 5.99 | 386.7 |