2025 Atlantic Coast Conference Leaders Total Defense - Games in August/September Only through 09/12/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Miami (FL) | 2 | 185 | 320 | 109 | 505 | 4.63 | 252.5 |
| 2 | Virginia Tech | 2 | 381 | 437 | 113 | 818 | 7.24 | 409.0 |
| 3 | California | 2 | 117 | 388 | 119 | 505 | 4.24 | 252.5 |
| 4 | Florida State | 2 | 192 | 346 | 121 | 538 | 4.45 | 269.0 |
| 5 | Virginia | 2 | 307 | 363 | 125 | 670 | 5.36 | 335.0 |
| 6 | Pittsburgh | 2 | 69 | 348 | 126 | 417 | 3.31 | 208.5 |
| 7 | Boston College | 2 | 165 | 383 | 130 | 548 | 4.22 | 274.0 |
| 8 | Louisville | 2 | 200 | 213 | 131 | 413 | 3.15 | 206.5 |
| 9 | Stanford | 2 | 253 | 385 | 132 | 638 | 4.83 | 319.0 |
| 10 | Clemson | 2 | 186 | 471 | 133 | 657 | 4.94 | 328.5 |
| 11 | Duke | 2 | 286 | 408 | 135 | 694 | 5.14 | 347.0 |
| 12 | Georgia Tech | 2 | 263 | 368 | 137 | 631 | 4.61 | 315.5 |
| 13 | North Carolina | 2 | 279 | 534 | 143 | 813 | 5.69 | 406.5 |
| 14 | SMU | 2 | 268 | 684 | 172 | 952 | 5.53 | 476.0 |
| 15 | NC State | 3 | 346 | 892 | 206 | 1238 | 6.01 | 412.7 |
| 16 | Wake Forest | 3 | 397 | 554 | 228 | 951 | 4.17 | 317.0 |
| 17 | Syracuse | 3 | 495 | 822 | 229 | 1317 | 5.75 | 439.0 |