2025 Atlantic Coast Conference Leaders Total Defense - Games in August/September Only through 10/24/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Miami (FL) | 4 | 305 | 673 | 229 | 978 | 4.27 | 244.5 |
| 2 | Louisville | 4 | 470 | 603 | 236 | 1073 | 4.55 | 268.3 |
| 3 | Florida State | 4 | 446 | 738 | 260 | 1184 | 4.55 | 296.0 |
| 3 | Boston College | 4 | 496 | 823 | 260 | 1319 | 5.07 | 329.8 |
| 5 | North Carolina | 4 | 546 | 832 | 272 | 1378 | 5.07 | 344.5 |
| 6 | Clemson | 4 | 487 | 961 | 280 | 1448 | 5.17 | 362.0 |
| 7 | Virginia Tech | 5 | 689 | 1095 | 291 | 1784 | 6.13 | 356.8 |
| 8 | California | 5 | 560 | 976 | 299 | 1536 | 5.14 | 307.2 |
| 9 | Pittsburgh | 4 | 304 | 947 | 301 | 1251 | 4.16 | 312.8 |
| 10 | Wake Forest | 4 | 560 | 802 | 313 | 1362 | 4.35 | 340.5 |
| 11 | SMU | 4 | 459 | 1338 | 314 | 1797 | 5.72 | 449.3 |
| 12 | Virginia | 5 | 657 | 1111 | 315 | 1768 | 5.61 | 353.6 |
| 13 | NC State | 5 | 724 | 1338 | 334 | 2062 | 6.17 | 412.4 |
| 14 | Duke | 5 | 698 | 1271 | 336 | 1969 | 5.86 | 393.8 |
| 15 | Stanford | 5 | 566 | 1575 | 345 | 2141 | 6.21 | 428.2 |
| 16 | Georgia Tech | 5 | 831 | 952 | 350 | 1783 | 5.09 | 356.6 |
| 17 | Syracuse | 5 | 870 | 1453 | 377 | 2323 | 6.16 | 464.6 |