2025 Big 12 Conference Leaders Total Defense - Games on the Road/Neutral Site Only through 09/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Houston | 1 | 177 | 51 | 66 | 228 | 3.45 | 228.0 |
| 2 | TCU | 1 | 50 | 172 | 49 | 222 | 4.53 | 222.0 |
| 3 | Colorado | 1 | 209 | 222 | 77 | 431 | 5.60 | 431.0 |
| 4 | Cincinnati | 1 | 110 | 243 | 78 | 353 | 4.53 | 353.0 |
| 5 | Utah | 2 | 205 | 244 | 107 | 449 | 4.20 | 224.5 |
| 6 | West Virginia | 1 | 182 | 247 | 79 | 429 | 5.43 | 429.0 |
| 7 | Arizona State | 1 | 66 | 279 | 63 | 345 | 5.48 | 345.0 |
| 8 | Baylor | 1 | 163 | 295 | 66 | 458 | 6.94 | 458.0 |
| 9 | Oklahoma State | 1 | 312 | 319 | 62 | 631 | 10.18 | 631.0 |
| 10 | Kansas | 1 | 261 | 334 | 86 | 595 | 6.92 | 595.0 |
| 11 | Kansas State | 2 | 364 | 361 | 153 | 725 | 4.74 | 362.5 |
| 12 | Iowa State | 2 | 270 | 495 | 130 | 765 | 5.88 | 382.5 |