2025 Big 12 Conference Leaders Total Defense - Games Lost Only through 09/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 1 | 312 | 319 | 62 | 631 | 10.18 | 631.0 |
| 2 | Arizona State | 1 | 66 | 279 | 63 | 345 | 5.48 | 345.0 |
| 3 | Baylor | 1 | 307 | 108 | 69 | 415 | 6.01 | 415.0 |
| 4 | Cincinnati | 1 | 110 | 243 | 78 | 353 | 4.53 | 353.0 |
| 5 | West Virginia | 1 | 182 | 247 | 79 | 429 | 5.43 | 429.0 |
| 6 | Kansas | 1 | 261 | 334 | 86 | 595 | 6.92 | 595.0 |
| 7 | Colorado | 2 | 529 | 365 | 145 | 894 | 6.17 | 447.0 |
| 8 | Kansas State | 3 | 601 | 456 | 235 | 1057 | 4.50 | 352.3 |