2025 Big 12 Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 09/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Kansas State | 1 | 130 | 183 | 74 | 313 | 4.23 | 313.0 |
| 2 | Baylor | 1 | 307 | 108 | 69 | 415 | 6.01 | 415.0 |
| 3 | Colorado | 1 | 320 | 143 | 68 | 463 | 6.81 | 463.0 |
| 4 | Kansas | 1 | 261 | 334 | 86 | 595 | 6.92 | 595.0 |
| 5 | Oklahoma State | 1 | 312 | 319 | 62 | 631 | 10.18 | 631.0 |