2025 Big 12 Conference Leaders Opponent First Downs - Games Lost Only through 09/06/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Baylor | 1 | 21 | 3 | 1 | 25 | 25.0 |
| 2 | Colorado | 1 | 17 | 8 | 2 | 27 | 27.0 |
| 3 | Oklahoma State | 1 | 14 | 9 | 1 | 24 | 24.0 |
| 4 | West Virginia | 1 | 10 | 10 | 4 | 24 | 24.0 |
| 5 | Arizona State | 1 | 5 | 12 | 0 | 17 | 17.0 |
| 5 | Kansas State | 2 | 26 | 12 | 1 | 39 | 19.5 |
| 7 | Cincinnati | 1 | 10 | 13 | 0 | 23 | 23.0 |
| 8 | Kansas | 1 | 12 | 16 | 0 | 28 | 28.0 |