2025 Big 12 Conference Leaders Opponent First Downs - Games vs. Non-Conference Teams Only through 09/06/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | TCU | 1 | 3 | 7 | 0 | 10 | 10.0 |
| 1 | UCF | 2 | 20 | 7 | 4 | 31 | 15.5 |
| 3 | BYU | 2 | 5 | 9 | 1 | 15 | 7.5 |
| 3 | Houston | 2 | 13 | 9 | 1 | 23 | 11.5 |
| 5 | Iowa State | 2 | 12 | 11 | 4 | 27 | 13.5 |
| 5 | Baylor | 2 | 33 | 11 | 4 | 48 | 24.0 |
| 7 | Texas Tech | 2 | 7 | 12 | 2 | 21 | 10.5 |
| 7 | Oklahoma State | 2 | 22 | 12 | 3 | 37 | 18.5 |
| 9 | Utah | 2 | 9 | 14 | 3 | 26 | 13.0 |
| 10 | West Virginia | 2 | 12 | 15 | 5 | 32 | 16.0 |
| 11 | Arizona | 2 | 11 | 16 | 5 | 32 | 16.0 |
| 11 | Kansas State | 2 | 24 | 16 | 3 | 43 | 21.5 |
| 13 | Colorado | 2 | 23 | 20 | 3 | 46 | 23.0 |
| 14 | Arizona State | 2 | 11 | 23 | 3 | 37 | 18.5 |
| 15 | Cincinnati | 2 | 16 | 24 | 4 | 44 | 22.0 |
| 16 | Kansas | 3 | 18 | 28 | 1 | 47 | 15.7 |