2025 Big 12 Conference Leaders Long All Purpose Plays - Games in October Only through 10/25/2025
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Cameron Dickey | Texas Tech | SO | RB | 4 | 3 | 3 | 3 | 2 | 1 | 0 | 0 |
| 2 | Parker Kingston | BYU | JR | WR | 4 | 4 | 3 | 2 | 1 | 1 | 0 | 0 |
| 2 | Amare Thomas | Houston | JR | WR | 4 | 5 | 3 | 2 | 1 | 0 | 0 | 0 |
| 2 | J'Koby Williams | Texas Tech | SO | RB | 4 | 4 | 2 | 2 | 1 | 1 | 1 | 1 |
| 5 | Trent Battle | TCU | SR | RB | 4 | 2 | 2 | 1 | 1 | 0 | 0 | 0 |
| 5 | Jayce Brown | Kansas St | JR | WR | 3 | 4 | 2 | 1 | 1 | 1 | 0 | 0 |
| 5 | Ryan Davis | Utah | SR | WR | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 5 | Brett Eskildsen | Iowa State | SO | WR | 3 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 5 | Byrd Ficklin | Utah | FR | QB | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 5 | LaDainian Fields | Okla St | FR | CB | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 5 | Rodney Fields Jr. | Okla St | FR | RB | 3 | 2 | 2 | 1 | 1 | 0 | 0 | 0 |
| 5 | Caleb Goodie | Cincinnati | JR | WR | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 5 | Carson Hansen | Iowa State | JR | RB | 2 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 5 | Nate Johnson | Utah | JR | ATH | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 5 | Eric McAlister | TCU | SR | WR | 4 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 5 | Matthew McDoom | Cincinnati | SR | CB | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 5 | Omarion Miller | Colorado | JR | WR | 3 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 5 | Jaden Nixon | UCF | SR | RB | 3 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 5 | Wayshawn Parker | Utah | SO | RB | 3 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
| 5 | Jacob Redding | Baylor | SO | S | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 5 | Chase Roberts | BYU | SR | WR | 4 | 3 | 3 | 1 | 1 | 1 | 1 | 0 |
| 5 | Jacob Rodriguez | Texas Tech | SR | LB | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 5 | Joe Royer | Cincinnati | SR | TE | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 5 | Tre Spivey | Arizona | SO | WR | 3 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |
| 5 | Conner Weigman | Houston | JR | QB | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |