2025 Conference USA Leaders Opponent First Downs - Games vs. Conference Teams Only through 10/08/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Liberty | 2 | 19 | 7 | 1 | 27 | 13.5 |
| 2 | Louisiana Tech | 2 | 7 | 18 | 3 | 28 | 14.0 |
| 3 | Delaware | 2 | 10 | 20 | 0 | 30 | 15.0 |
| 4 | Middle Tennessee State | 2 | 14 | 19 | 3 | 36 | 18.0 |
| 5 | UTEP | 2 | 17 | 16 | 5 | 38 | 19.0 |
| 6 | Jacksonville State | 1 | 10 | 10 | 0 | 20 | 20.0 |
| 7 | Western Kentucky | 3 | 21 | 33 | 8 | 62 | 20.7 |
| 8 | Sam Houston State | 2 | 9 | 32 | 5 | 46 | 23.0 |
| 8 | New Mexico State | 2 | 22 | 21 | 3 | 46 | 23.0 |
| 10 | Missouri State | 2 | 15 | 26 | 6 | 47 | 23.5 |
| 11 | Kennesaw State | 1 | 9 | 14 | 1 | 24 | 24.0 |
| 11 | FIU | 1 | 10 | 10 | 4 | 24 | 24.0 |