2021 Big Ten Conference Leaders Total Defense - Games in November Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Illinois | 3 | 379 | 406 | 208 | 785 | 3.77 | 261.7 |
| 2 | Michigan | 4 | 461 | 883 | 302 | 1344 | 4.45 | 336.0 |
| 3 | Minnesota | 4 | 459 | 534 | 219 | 993 | 4.53 | 248.3 |
| 4 | Wisconsin | 4 | 336 | 787 | 240 | 1123 | 4.68 | 280.8 |
| 5 | Penn State | 4 | 460 | 949 | 292 | 1409 | 4.83 | 352.3 |
| 6 | Iowa | 4 | 475 | 936 | 284 | 1411 | 4.97 | 352.8 |
| 7 | Indiana | 4 | 768 | 801 | 264 | 1569 | 5.94 | 392.3 |
| 8 | Maryland | 4 | 602 | 1165 | 293 | 1767 | 6.03 | 441.8 |
| 9 | Purdue | 4 | 646 | 943 | 263 | 1589 | 6.04 | 397.3 |
| 10 | Ohio State | 4 | 567 | 982 | 256 | 1549 | 6.05 | 387.3 |
| 11 | Rutgers | 4 | 795 | 1021 | 293 | 1816 | 6.20 | 454.0 |
| 12 | Nebraska | 3 | 528 | 728 | 197 | 1256 | 6.38 | 418.7 |
| 13 | Michigan State | 4 | 426 | 1648 | 304 | 2074 | 6.82 | 518.5 |
| 14 | Northwestern | 4 | 720 | 1070 | 262 | 1790 | 6.83 | 447.5 |