2021 Ohio State Buckeyes Total Defense Split Stats through 01/10/2022
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 13 | 1648 | 3196 | 909 | 4844 | 5.33 | 372.6 |
| at Home | 7 | 664 | 2001 | 515 | 2665 | 5.17 | 380.7 |
| on Road/Neutral Site | 6 | 984 | 1195 | 394 | 2179 | 5.53 | 363.2 |
| in Wins | 11 | 1082 | 2770 | 775 | 3852 | 4.97 | 350.2 |
| in Losses | 2 | 566 | 426 | 134 | 992 | 7.40 | 496.0 |
| vs. Conference | 9 | 1004 | 2142 | 612 | 3146 | 5.14 | 349.6 |
| vs. Non-Conference | 4 | 644 | 1054 | 297 | 1698 | 5.72 | 424.5 |
| vs. Ranked (AP) | 4 | 858 | 821 | 261 | 1679 | 6.43 | 419.8 |
| vs. Unranked (AP) | 9 | 790 | 2375 | 648 | 3165 | 4.88 | 351.7 |
| vs. FBS (I-A) | 13 | 1648 | 3196 | 909 | 4844 | 5.33 | 372.6 |
| vs. FCS (I-AA) | 0 | 0 | 0 | 0 | 0 | - | - |
| vs. FBS Winning | 9 | 1314 | 2480 | 645 | 3794 | 5.88 | 421.6 |
| vs. FBS Non-Winning | 4 | 334 | 716 | 264 | 1050 | 3.98 | 262.5 |
| vs. FBS Power 5 | 11 | 1499 | 2615 | 753 | 4114 | 5.46 | 374.0 |
| vs. FBS non-Power 5 | 2 | 149 | 581 | 156 | 730 | 4.68 | 365.0 |
| in August/September | 4 | 621 | 1022 | 304 | 1643 | 5.40 | 410.8 |
| in October | 4 | 234 | 955 | 281 | 1189 | 4.23 | 297.3 |
| in November | 4 | 567 | 982 | 256 | 1549 | 6.05 | 387.3 |
| in December/January | 1 | 226 | 237 | 68 | 463 | 6.81 | 463.0 |