2021 Northwestern Wildcats Total Defense Split Stats through 01/10/2022
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 12 | 2559 | 2598 | 839 | 5157 | 6.15 | 429.8 |
| at Home | 6 | 1092 | 961 | 389 | 2053 | 5.28 | 342.2 |
| on Road/Neutral Site | 6 | 1467 | 1637 | 450 | 3104 | 6.90 | 517.3 |
| in Wins | 3 | 273 | 466 | 186 | 739 | 3.97 | 246.3 |
| in Losses | 9 | 2286 | 2132 | 653 | 4418 | 6.77 | 490.9 |
| vs. Conference | 9 | 2138 | 1941 | 621 | 4079 | 6.57 | 453.2 |
| vs. Non-Conference | 3 | 421 | 657 | 218 | 1078 | 4.94 | 359.3 |
| vs. Ranked (AP) | 3 | 805 | 524 | 219 | 1329 | 6.07 | 443.0 |
| vs. Unranked (AP) | 9 | 1754 | 2074 | 620 | 3828 | 6.17 | 425.3 |
| vs. FBS (I-A) | 11 | 2528 | 2460 | 782 | 4988 | 6.38 | 453.5 |
| vs. FCS (I-AA) | 1 | 31 | 138 | 57 | 169 | 2.96 | 169.0 |
| vs. FBS Winning | 6 | 1431 | 1310 | 420 | 2741 | 6.53 | 456.8 |
| vs. FBS Non-Winning | 5 | 1097 | 1150 | 362 | 2247 | 6.21 | 449.4 |
| vs. FBS Power 5 | 10 | 2349 | 2291 | 719 | 4640 | 6.45 | 464.0 |
| vs. FBS non-Power 5 | 1 | 179 | 169 | 63 | 348 | 5.52 | 348.0 |
| in August/September | 4 | 747 | 842 | 281 | 1589 | 5.65 | 397.3 |
| in October | 4 | 1092 | 686 | 296 | 1778 | 6.01 | 444.5 |
| in November | 4 | 720 | 1070 | 262 | 1790 | 6.83 | 447.5 |
| in December/January | 0 | 0 | 0 | 0 | 0 | - | - |