2021 Michigan Wolverines Total Defense Split Stats through 01/10/2022
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 14 | 1770 | 2862 | 939 | 4632 | 4.93 | 330.9 |
| at Home | 7 | 804 | 1301 | 458 | 2105 | 4.60 | 300.7 |
| on Road/Neutral Site | 7 | 966 | 1561 | 481 | 2527 | 5.25 | 361.0 |
| in Wins | 12 | 1381 | 2335 | 807 | 3716 | 4.60 | 309.7 |
| in Losses | 2 | 389 | 527 | 132 | 916 | 6.94 | 458.0 |
| vs. Conference | 10 | 1243 | 2001 | 682 | 3244 | 4.76 | 324.4 |
| vs. Non-Conference | 4 | 527 | 861 | 257 | 1388 | 5.40 | 347.0 |
| vs. Ranked (AP) | 4 | 557 | 1096 | 282 | 1653 | 5.86 | 413.3 |
| vs. Unranked (AP) | 10 | 1213 | 1766 | 657 | 2979 | 4.53 | 297.9 |
| vs. FBS (I-A) | 14 | 1770 | 2862 | 939 | 4632 | 4.93 | 330.9 |
| vs. FCS (I-AA) | 0 | 0 | 0 | 0 | 0 | - | - |
| vs. FBS Winning | 9 | 1177 | 1901 | 622 | 3078 | 4.95 | 342.0 |
| vs. FBS Non-Winning | 5 | 593 | 961 | 317 | 1554 | 4.90 | 310.8 |
| vs. FBS Power 5 | 12 | 1483 | 2625 | 817 | 4108 | 5.03 | 342.3 |
| vs. FBS non-Power 5 | 2 | 287 | 237 | 122 | 524 | 4.30 | 262.0 |
| in August/September | 4 | 533 | 686 | 264 | 1219 | 4.62 | 304.8 |
| in October | 4 | 482 | 787 | 236 | 1269 | 5.38 | 317.3 |
| in November | 4 | 461 | 883 | 302 | 1344 | 4.45 | 336.0 |
| in December/January | 2 | 294 | 506 | 137 | 800 | 5.84 | 400.0 |