2021 Big Ten Conference Leaders Total Defense - All Games through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Wisconsin | 13 | 793 | 2266 | 746 | 3059 | 4.10 | 235.3 |
| 2 | Iowa | 14 | 1602 | 3003 | 976 | 4605 | 4.72 | 328.9 |
| 3 | Penn State | 13 | 1999 | 2598 | 965 | 4597 | 4.76 | 353.6 |
| 4 | Minnesota | 13 | 1268 | 2356 | 745 | 3624 | 4.86 | 278.8 |
| 5 | Michigan | 14 | 1770 | 2862 | 939 | 4632 | 4.93 | 330.9 |
| 6 | Illinois | 12 | 1822 | 2582 | 840 | 4404 | 5.24 | 367.0 |
| 7 | Nebraska | 12 | 1763 | 2629 | 828 | 4392 | 5.30 | 366.0 |
| 8 | Ohio State | 13 | 1648 | 3196 | 909 | 4844 | 5.33 | 372.6 |
| 9 | Purdue | 13 | 2035 | 2713 | 857 | 4748 | 5.54 | 365.2 |
| 10 | Michigan State | 13 | 1511 | 4222 | 1025 | 5733 | 5.59 | 441.0 |
| 11 | Indiana | 12 | 1777 | 2828 | 818 | 4605 | 5.63 | 383.8 |
| 12 | Maryland | 13 | 2012 | 3234 | 910 | 5246 | 5.76 | 403.5 |
| 13 | Rutgers | 13 | 2093 | 3054 | 866 | 5147 | 5.94 | 395.9 |
| 14 | Northwestern | 12 | 2559 | 2598 | 839 | 5157 | 6.15 | 429.8 |