2021 Big Ten Conference Leaders Total Defense - Games at Home Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Purdue | 6 | 906 | 1029 | 369 | 1935 | 5.24 | 322.5 |
| 2 | Northwestern | 6 | 1092 | 961 | 389 | 2053 | 5.28 | 342.2 |
| 3 | Rutgers | 6 | 1297 | 1504 | 396 | 2801 | 7.07 | 466.8 |
| 4 | Indiana | 6 | 883 | 1197 | 401 | 2080 | 5.19 | 346.7 |
| 5 | Minnesota | 7 | 789 | 1382 | 402 | 2171 | 5.40 | 310.1 |
| 6 | Wisconsin | 7 | 547 | 1271 | 404 | 1818 | 4.50 | 259.7 |
| 7 | Michigan | 7 | 804 | 1301 | 458 | 2105 | 4.60 | 300.7 |
| 8 | Michigan State | 6 | 729 | 1942 | 469 | 2671 | 5.70 | 445.2 |
| 9 | Penn State | 7 | 964 | 1176 | 486 | 2140 | 4.40 | 305.7 |
| 10 | Maryland | 7 | 857 | 1905 | 494 | 2762 | 5.59 | 394.6 |
| 11 | Illinois | 7 | 1328 | 1434 | 503 | 2762 | 5.49 | 394.6 |
| 12 | Iowa | 7 | 698 | 1522 | 505 | 2220 | 4.40 | 317.1 |
| 13 | Ohio State | 7 | 664 | 2001 | 515 | 2665 | 5.17 | 380.7 |
| 14 | Nebraska | 7 | 897 | 1714 | 522 | 2611 | 5.00 | 373.0 |