2021 Big 12 Conference Leaders Total Offense - Games on the Road/Neutral Site Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brock Purdy | Iowa State | SR | QB | 7 | 116 | 1785 | 278 | 1901 | 6.84 | 271.6 |
| 2 | Spencer Sanders | Okla St | JR | QB | 7 | 309 | 1526 | 317 | 1835 | 5.79 | 262.1 |
| 3 | Jarret Doege | WVU | SR | QB | 7 | -80 | 1509 | 263 | 1429 | 5.43 | 204.1 |
| 4 | Caleb Williams | Oklahoma | FR | QB | 6 | 238 | 1044 | 178 | 1282 | 7.20 | 213.7 |
| 5 | Skylar Thompson | Kansas St | SR | QB | 4 | 18 | 953 | 120 | 971 | 8.09 | 242.8 |
| 6 | Gerry Bohanon | Baylor | JR | QB | 6 | 110 | 920 | 164 | 1030 | 6.28 | 171.7 |
| 7 | Casey Thompson | Texas | JR | QB | 6 | 86 | 898 | 150 | 984 | 6.56 | 164.0 |
| 8 | Henry Colombi | Texas Tech | SR | QB | 4 | 22 | 791 | 107 | 813 | 7.60 | 203.3 |
| 9 | Donovan Smith | Texas Tech | FR | QB | 6 | 105 | 783 | 106 | 888 | 8.38 | 148.0 |
| 10 | Max Duggan | TCU | JR | QB | 4 | 108 | 739 | 116 | 847 | 7.30 | 211.8 |
| 11 | Jason Bean | Kansas | JR | QB | 5 | 198 | 642 | 129 | 840 | 6.51 | 168.0 |
| 12 | Jalon Daniels | Kansas | SO | QB | 3 | 71 | 506 | 84 | 577 | 6.87 | 192.3 |
| 13 | Spencer Rattler | Oklahoma | SO | QB | 3 | 6 | 390 | 62 | 396 | 6.39 | 132.0 |
| 14 | Blake Shapen | Baylor | FR | QB | 3 | 35 | 317 | 63 | 352 | 5.59 | 117.3 |
| 15 | Tyler Shough | Texas Tech | JR | QB | 2 | 4 | 299 | 42 | 303 | 7.21 | 151.5 |
| 16 | Hudson Card | Texas | FR | QB | 3 | 6 | 285 | 71 | 291 | 4.10 | 97.0 |
| 17 | Chandler Morris | TCU | FR | QB | 2 | 13 | 236 | 48 | 249 | 5.19 | 124.5 |
| 18 | Jaren Lewis | Kansas St | SO | QB | 1 | 3 | 148 | 24 | 151 | 6.29 | 151.0 |
| 19 | Will Howard | Kansas St | SO | QB | 4 | 119 | 128 | 40 | 247 | 6.18 | 61.8 |
| 20 | Sam Jackson | TCU | FR | QB | 1 | 4 | 77 | 5 | 81 | 16.20 | 81.0 |
| 21 | Garrett Greene | WVU | FR | QB | 5 | 133 | 60 | 30 | 193 | 6.43 | 38.6 |
| 22 | Hunter Dekkers | Iowa State | FR | QB | 2 | 14 | 50 | 17 | 64 | 3.76 | 32.0 |
| 23 | Miles Kendrick | Kansas | SR | QB | 2 | 32 | 41 | 19 | 73 | 3.84 | 36.5 |
| 24 | Brennan Presley | Okla St | SO | WR | 7 | 22 | 6 | 6 | 28 | 4.67 | 4.0 |