2021 Iowa State Cyclones Total Offense Split Stats through 01/10/2022
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 13 | 2089 | 3430 | 857 | 5519 | 6.44 | 424.5 |
| at Home | 6 | 1034 | 1595 | 382 | 2629 | 6.88 | 438.2 |
| on Road/Neutral Site | 7 | 1055 | 1835 | 475 | 2890 | 6.08 | 412.9 |
| in Wins | 7 | 1341 | 1860 | 439 | 3201 | 7.29 | 457.3 |
| in Losses | 6 | 748 | 1570 | 418 | 2318 | 5.55 | 386.3 |
| vs. Conference | 9 | 1616 | 2466 | 600 | 4082 | 6.80 | 453.6 |
| vs. Non-Conference | 4 | 473 | 964 | 257 | 1437 | 5.59 | 359.3 |
| vs. Ranked (AP) | 5 | 487 | 1336 | 356 | 1823 | 5.12 | 364.6 |
| vs. Unranked (AP) | 8 | 1602 | 2094 | 501 | 3696 | 7.38 | 462.0 |
| vs. FBS (I-A) | 12 | 1953 | 3231 | 797 | 5184 | 6.50 | 432.0 |
| vs. FCS (I-AA) | 1 | 136 | 199 | 60 | 335 | 5.58 | 335.0 |
| vs. FBS Winning | 7 | 786 | 1900 | 483 | 2686 | 5.56 | 383.7 |
| vs. FBS Non-Winning | 5 | 1167 | 1331 | 314 | 2498 | 7.96 | 499.6 |
| vs. FBS Power 5 | 11 | 1769 | 2922 | 730 | 4691 | 6.43 | 426.5 |
| vs. FBS non-Power 5 | 1 | 184 | 309 | 67 | 493 | 7.36 | 493.0 |
| in August/September | 4 | 623 | 1023 | 270 | 1646 | 6.10 | 411.5 |
| in October | 4 | 806 | 974 | 247 | 1780 | 7.21 | 445.0 |
| in November | 4 | 594 | 1229 | 280 | 1823 | 6.51 | 455.8 |
| in December/January | 1 | 66 | 204 | 60 | 270 | 4.50 | 270.0 |