2021 Big 12 Conference Leaders Total Offense - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Spencer Sanders | Okla St | JR | QB | 9 | 520 | 2079 | 394 | 2599 | 6.60 | 288.8 |
| 2 | Jarret Doege | WVU | SR | QB | 8 | -109 | 1879 | 323 | 1770 | 5.48 | 221.3 |
| 3 | Brock Purdy | Iowa State | SR | QB | 7 | 14 | 1757 | 287 | 1771 | 6.17 | 253.0 |
| 4 | Casey Thompson | Texas | JR | QB | 8 | 89 | 1420 | 202 | 1509 | 7.47 | 188.6 |
| 5 | Caleb Williams | Oklahoma | FR | QB | 6 | 157 | 1143 | 186 | 1300 | 6.99 | 216.7 |
| 6 | Donovan Smith | Texas Tech | FR | QB | 6 | 98 | 1118 | 181 | 1216 | 6.72 | 202.7 |
| 7 | Max Duggan | TCU | JR | QB | 5 | 138 | 1015 | 154 | 1153 | 7.49 | 230.6 |
| 8 | Skylar Thompson | Kansas St | SR | QB | 4 | -50 | 990 | 145 | 940 | 6.48 | 235.0 |
| 9 | Gerry Bohanon | Baylor | JR | QB | 6 | 206 | 790 | 172 | 996 | 5.79 | 166.0 |
| 10 | Jason Bean | Kansas | JR | QB | 7 | 291 | 766 | 185 | 1057 | 5.71 | 151.0 |
| 11 | Chandler Morris | TCU | FR | QB | 3 | 83 | 697 | 100 | 780 | 7.80 | 260.0 |
| 12 | Blake Shapen | Baylor | FR | QB | 3 | 59 | 571 | 104 | 630 | 6.06 | 210.0 |
| 13 | Hudson Card | Texas | FR | QB | 5 | 0 | 386 | 81 | 386 | 4.77 | 77.2 |
| 14 | Spencer Rattler | Oklahoma | SO | QB | 4 | 15 | 355 | 48 | 370 | 7.71 | 92.5 |
| 15 | Tyler Shough | Texas Tech | JR | QB | 1 | -2 | 231 | 30 | 229 | 7.63 | 229.0 |
| 16 | Henry Colombi | Texas Tech | SR | QB | 2 | 17 | 225 | 40 | 242 | 6.05 | 121.0 |
| 17 | Will Howard | Kansas St | SO | QB | 2 | 84 | 173 | 37 | 257 | 6.95 | 128.5 |
| 18 | Jaren Lewis | Kansas St | SO | QB | 3 | 3 | 154 | 28 | 157 | 5.61 | 52.3 |
| 18 | Jalon Daniels | Kansas | SO | QB | 3 | -8 | 154 | 29 | 146 | 5.03 | 48.7 |
| 20 | Hunter Dekkers | Iowa State | FR | QB | 2 | 2 | 143 | 26 | 145 | 5.58 | 72.5 |
| 21 | Miles Kendrick | Kansas | SR | QB | 5 | 73 | 106 | 31 | 179 | 5.77 | 35.8 |
| 22 | Sam Jackson | TCU | FR | QB | 1 | 4 | 77 | 5 | 81 | 16.20 | 81.0 |
| 23 | Garrett Greene | WVU | FR | QB | 6 | 108 | 73 | 42 | 181 | 4.31 | 30.2 |
| 24 | Taye Barber | TCU | SR | WR | 7 | 7 | 7 | 4 | 14 | 3.50 | 2.0 |
| 25 | Brennan Presley | Okla St | SO | WR | 9 | 5 | 6 | 4 | 11 | 2.75 | 1.2 |
| 26 | Roschon Johnson | Texas | JR | RB | 8 | 321 | 2 | 66 | 323 | 4.89 | 40.4 |