2021 Big 12 Conference Leaders All Purpose - Games Lost Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Kwamie Lassiter II | Kansas | SR | WR | 10 | 0 | 573 | 96 | 0 | 55 | 669 | 12.2 | 66.9 |
| 2 | Jaylin Noel | Iowa State | FR | WR | 6 | 0 | 182 | 51 | 134 | 33 | 367 | 11.1 | 61.2 |
| 3 | Derius Davis | TCU | SR | WR | 7 | -10 | 206 | 43 | 473 | 45 | 712 | 15.8 | 101.7 |
| 4 | D'Shawn Jamison | Texas | SR | DB | 7 | 0 | 0 | 40 | 255 | 21 | 295 | 14.0 | 42.1 |
| 5 | Myles Price | Texas Tech | SO | WR | 5 | 26 | 215 | 27 | 0 | 23 | 268 | 11.7 | 53.6 |
| 6 | DeMarvion Overshown | Texas | SR | LB | 7 | 0 | 0 | 17 | 0 | 1 | 17 | 17.0 | 2.4 |
| 7 | Isaiah Esdale | WVU | SR | WR | 4 | 0 | 198 | 16 | 0 | 18 | 214 | 11.9 | 53.5 |
| 8 | Tarique Milton | Iowa State | SR | WR | 5 | 0 | 91 | 11 | 0 | 5 | 102 | 20.4 | 20.4 |
| 9 | Marcus Washington | Texas | JR | WR | 7 | 0 | 240 | 5 | 0 | 16 | 245 | 15.3 | 35.0 |
| 9 | Adrian Frye | Texas Tech | SR | DB | 4 | 0 | 0 | 5 | 0 | 4 | 5 | 1.3 | 1.3 |
| 11 | Marvin Mims | Oklahoma | SO | WR | 2 | 15 | 21 | 4 | 0 | 6 | 40 | 6.7 | 20.0 |