2021 Big 12 Conference Leaders All Purpose - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Trestan Ebner | Baylor | SR | RB | 8 | 324 | 220 | 91 | 392 | 122 | 1027 | 8.4 | 128.4 |
| 2 | D'Shawn Jamison | Texas | SR | DB | 8 | 0 | 0 | 69 | 273 | 22 | 342 | 15.5 | 42.8 |
| 3 | Derius Davis | TCU | SR | WR | 7 | 4 | 294 | 56 | 362 | 42 | 716 | 17.0 | 102.3 |
| 4 | Jaylin Noel | Iowa State | FR | WR | 7 | 0 | 230 | 51 | 129 | 39 | 410 | 10.5 | 58.6 |
| 5 | Kwamie Lassiter II | Kansas | SR | WR | 7 | 0 | 328 | 50 | 0 | 32 | 378 | 11.8 | 54.0 |
| 6 | Adrian Frye | Texas Tech | SR | DB | 5 | 0 | 0 | 47 | 0 | 9 | 47 | 5.2 | 9.4 |
| 7 | Isaiah Esdale | WVU | SR | WR | 5 | 0 | 259 | 42 | 0 | 26 | 301 | 11.6 | 60.2 |
| 8 | Brennan Presley | Okla St | SO | WR | 9 | 5 | 385 | 40 | 298 | 50 | 728 | 14.6 | 80.9 |
| 9 | Marvin Mims | Oklahoma | SO | WR | 6 | 15 | 306 | 28 | 20 | 19 | 369 | 19.4 | 61.5 |
| 10 | Myles Price | Texas Tech | SO | WR | 6 | 25 | 346 | 27 | 0 | 30 | 398 | 13.3 | 66.3 |
| 11 | Xavier Worthy | Texas | FR | WR | 8 | 7 | 666 | 18 | 18 | 37 | 709 | 19.2 | 88.6 |
| 12 | DeMarvion Overshown | Texas | SR | LB | 7 | 0 | 0 | 17 | 0 | 1 | 17 | 17.0 | 2.4 |
| 13 | McLane Mannix | Texas Tech | SR | WR | 6 | 1 | 73 | 16 | 0 | 6 | 90 | 15.0 | 15.0 |
| 14 | Tarique Milton | Iowa State | SR | WR | 6 | 0 | 79 | 11 | 0 | 7 | 90 | 12.9 | 15.0 |