2021 Big 12 Conference Leaders Interceptions - Games at Home Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Marquis Waters | Texas Tech | SR | DB | 2 | 1 | 72 | 1 | 0.50 |
| 1 | Josh Thompson | Texas | SR | DB | 5 | 1 | 27 | 1 | 0.20 |
| 1 | Gavin Potter | Kansas | JR | LB | 6 | 1 | 28 | 1 | 0.17 |