2021 Conference USA Leaders Total Offense - Games in December/January Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 2 | 206 | 999 | 151 | 1205 | 7.98 | 602.5 |
| 2 | UTSA | 2 | 421 | 507 | 146 | 928 | 6.36 | 464.0 |
| 3 | Middle Tennessee | 1 | 159 | 276 | 85 | 435 | 5.12 | 435.0 |
| 4 | UAB | 1 | 223 | 189 | 66 | 412 | 6.24 | 412.0 |
| 5 | UTEP | 1 | 98 | 303 | 58 | 401 | 6.91 | 401.0 |
| 6 | North Texas | 1 | 89 | 228 | 64 | 317 | 4.95 | 317.0 |
| 7 | Marshall | 1 | 187 | 99 | 56 | 286 | 5.11 | 286.0 |
| 8 | Old Dominion | 1 | 71 | 176 | 47 | 247 | 5.26 | 247.0 |