2021 Conference USA Leaders Total Offense - Games vs. FCS (I-AA) Teams Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Marshall | 1 | 237 | 463 | 100 | 700 | 7.00 | 700.0 |
| 2 | Rice | 1 | 349 | 271 | 75 | 620 | 8.27 | 620.0 |
| 3 | Florida International | 1 | 318 | 276 | 49 | 594 | 12.12 | 594.0 |
| 4 | Western Kentucky | 1 | 109 | 478 | 61 | 587 | 9.62 | 587.0 |
| 5 | Old Dominion | 1 | 358 | 214 | 83 | 572 | 6.89 | 572.0 |
| 6 | Florida Atlantic | 1 | 246 | 301 | 95 | 547 | 5.76 | 547.0 |
| 7 | North Texas | 1 | 345 | 182 | 76 | 527 | 6.93 | 527.0 |
| 8 | UAB | 1 | 147 | 370 | 60 | 517 | 8.62 | 517.0 |
| 9 | UTEP | 1 | 299 | 183 | 74 | 482 | 6.51 | 482.0 |
| 10 | Charlotte | 1 | 306 | 168 | 71 | 474 | 6.68 | 474.0 |
| 11 | Louisiana Tech | 1 | 199 | 250 | 70 | 449 | 6.41 | 449.0 |
| 12 | Southern Mississippi | 1 | 290 | 149 | 73 | 439 | 6.01 | 439.0 |
| 13 | UTSA | 1 | 106 | 321 | 61 | 427 | 7.00 | 427.0 |
| 14 | Middle Tennessee | 1 | 96 | 248 | 60 | 344 | 5.73 | 344.0 |