2018 Atlantic Coast Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina | 3 | 513 | 709 | 233 | 1222 | 5.24 | 407.3 |
| 2 | Boston College | 4 | 530 | 873 | 283 | 1403 | 4.96 | 350.8 |
| 3 | Duke | 5 | 586 | 1028 | 360 | 1614 | 4.48 | 322.8 |
| 4 | Clemson | 6 | 594 | 1501 | 403 | 2095 | 5.20 | 349.2 |
| 5 | Virginia | 5 | 627 | 954 | 305 | 1581 | 5.18 | 316.2 |
| 6 | Miami (Florida) | 5 | 648 | 653 | 303 | 1301 | 4.29 | 260.2 |
| 7 | Pittsburgh | 5 | 694 | 1139 | 321 | 1833 | 5.71 | 366.6 |
| 8 | Florida State | 4 | 703 | 1074 | 294 | 1777 | 6.04 | 444.3 |
| 9 | North Carolina State | 5 | 756 | 927 | 309 | 1683 | 5.45 | 336.6 |
| 10 | Syracuse | 5 | 778 | 1412 | 354 | 2190 | 6.19 | 438.0 |
| 11 | Virginia Tech | 5 | 826 | 1424 | 347 | 2250 | 6.48 | 450.0 |
| 12 | Georgia Tech | 5 | 904 | 900 | 329 | 1804 | 5.48 | 360.8 |
| 12 | Louisville | 4 | 904 | 855 | 281 | 1759 | 6.26 | 439.8 |
| 14 | Wake Forest | 5 | 935 | 1225 | 394 | 2160 | 5.48 | 432.0 |