2018 Atlantic Coast Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 12 | 1159 | 2578 | 840 | 3737 | 4.45 | 311.4 |
| 2 | Florida State | 9 | 1351 | 2404 | 739 | 3755 | 5.08 | 417.2 |
| 3 | North Carolina State | 9 | 1355 | 2607 | 610 | 3962 | 6.50 | 440.2 |
| 4 | Boston College | 9 | 1405 | 2398 | 721 | 3803 | 5.27 | 422.6 |
| 5 | Syracuse | 9 | 1480 | 2298 | 671 | 3778 | 5.63 | 419.8 |
| 6 | Virginia | 10 | 1561 | 1793 | 635 | 3354 | 5.28 | 335.4 |
| 7 | Wake Forest | 8 | 1568 | 2234 | 621 | 3802 | 6.12 | 475.3 |
| 8 | Georgia Tech | 10 | 1694 | 2146 | 592 | 3840 | 6.49 | 384.0 |
| 9 | Miami (Florida) | 10 | 1704 | 1323 | 674 | 3027 | 4.49 | 302.7 |
| 10 | Virginia Tech | 8 | 1908 | 1545 | 545 | 3453 | 6.34 | 431.6 |
| 11 | North Carolina | 9 | 2054 | 1927 | 671 | 3981 | 5.93 | 442.3 |
| 12 | Pittsburgh | 11 | 2116 | 2075 | 723 | 4191 | 5.80 | 381.0 |
| 13 | Duke | 10 | 2364 | 2117 | 766 | 4481 | 5.85 | 448.1 |
| 14 | Louisville | 10 | 2985 | 2178 | 700 | 5163 | 7.38 | 516.3 |